Endocrine Abstracts

We present two cases where, without measurement of cortisol binding globulin (CBG), interpretation of their 250mcg short synacthen test (SST) would have falsely suggested inadequate pituitary-adrenal reserve.A 62yr old woman was referred with an incidental finding of a pituitary adenoma. Pituitary function tests confirmed gonadotrophin and growth hormone deficiency. Initial and subsequent SSTs were normal (30min cortisol reater than 600nmol/L). Follow up...

Background: Vitamin D insufficiency is very common in general population and in patients with primary hyperparathyroidism (PHPT). Measurement of serum 25OHD (25hydroxy-vitamin D) is currently the best available test to assess vitamin D adequacy. However, it has a significant seasonal variation, and is difficult to define a serum 25OHD level that is sufficient for bone health, although a serum 25OHD above 50 nmol/l has been suggested.Previous studies conf...

The Royal College of Physicians guidelines (2007) on follow-up post radioiodine therapy for hyperthyroidism recommend thyroid function monitoring around weeks 6, 12, 26, 39, 52 and yearly thereafter in stable patients. We retrospectively analyzed data from 91 patients given radioiodine in 2005 who were followed-up locally comparing our practice with these standards. Fifteen percent of patients were lost to follow-up before year one with 40% of these not having their thyroid fu...